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Semaglutide, a glucagon like peptide 1 (GLP 1) receptor agonist, has well established weight loss benefits. Cagrilintide, a long acting analogue of the satiety hormone amylin, has shown promise for weight loss in early trials. The potential benefit Ozempic and Wegovy Linked to Rare Blindness Risk, Study Finds Two of the most anticipated studies this yearlarge scale, randomized, controlled, and double blinded trials of the popular obesity and diabetes drug semaglutide for Alzheimer's diseasehave unfortunately ended in a dud. An oral version Semaglutide for Medical Weight Loss: Myths vs. Facts Ozempic quiets hunger. The next drug may burn fuel. That's the shift hiding inside an April 2026 study almost no one read carefully. In clinic, the question I get most about Ozempic
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Best in 7 days
Best in 7 days
Best in 7 days
Best in 7 days
4.9 ★★★★★
Based on 2393 reviews
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Product Reviews
★★★★★ 5
Clean Ingredients & Leaves Teeth Feeling Smooth
Size: Pack of 1, 4 Ounce, Set name: B. Whitening
I’ve tried many natural toothpastes, and this one quickly became a favorite. The texture feels smooth, and my teeth feel really clean after brushing. I love that it contains nano hydroxyapatite and is fluoride-free, especially for sensitive teeth.
The flavor is fresh without being overpowering, and it doesn’t leave a weird aftertaste. It’s also gentle enough for everyday use and makes my teeth feel polished and healthy. Definitely worth trying if you want a cleaner alternative toothpaste.
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Reviewed in the United States on May 20, 2026
★★★★★ 5
Perfect Fluoride alternative
Size: Pack of 1, 4 Ounce, Set name: B. Whitening
I bought this because it's popular in other countries like Japan. America is so behind using fluoride, when it's been proven to cause pituitary gland problems. If you're looking for a fluoride-free toothpaste look no further.
It works well, you just unscrew and apply to your brush. Pro tip: use a sonic toothbrush and glide on your teeth at a 45° angle. Using this toothpaste for months, 2 minutes twice a day, has made my teeth visibly whiter.
The flavor is not super strong, so it's suitable for kids and really anyone. Super easy and simple to use, it works like regular toothpaste. Smells minty, it's fluoride-free, and medium sized. It'll last me about 2 months, which I find worth it.
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Reviewed in the United States on April 28, 2026
★★★★★ 4
Fluoride who?
Size: Pack of 3, 4 Ounce, Set name: B. Whitening
Great product definitely works better than your traditional fluoride or fluoride free toothpaste it actually combats plaque and strengthens the enamel of your teeth I have physically and visibly seen the difference not just in my teeth but gums. Tastes great cleans well clean ingredients the only downside is it's unfortunately very pricey and if you're buying for not just yourself but a family it can start to add up fast just something to consider before purchasing. I love the tube and cap design it's gentle on your gums and teeth and it has good ingredients making the minty flavor taste more natural rather than a synthetic mint flavor and this product actually whitens your teeth. keep in mind that this isn't a replacement for teeth whitening treatments and it's also not a replacement for good dental hygiene like flossing/brushing multiple times a day. If your suffering from serious Dental issues this will not cure it but it is an excellent alternative to fluoride toothpaste that provide little to no benefit for your actual oral and overall dental health. The reason for four not five stars is because of the price I think if they could continue making the same product got the same level of quality for a little less money it would be a five-star item
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Reviewed in the United States on March 8, 2026
★★★★★ 5
URGENT!!!! REALLY WORKS!!!! Fact ✔️
Size: Pack of 3, 4 Ounce, Set name: B. Whitening
I was immediately convinced this would work due to its ingredients, I had a previous filling fallout. So I immediately requested he apply another filling while I was getting some other dental work done, and the dentist said there was no rush to install, A new filling, showed me a picture. It looked great still white no cavities. In the high definition, microscope photo he showed me,It almost look like the inside of a white Jacuzzi tub with molded seat, I had the rest of the work done and didn’t get to go back soon enough, and the tooth started to bother me when something sweet would hit that spot and I looked in the mirror and it was starting to turn a light brownish color, I had just heard about HA toothpaste, I did some research and this is what I found
Hydroxyapatite = the SAME mineral your teeth are made of
• Your enamel is mostly this material (like 70–97% of tooth structure) 
• So instead of adding a chemical… it’s literally rebuilding with the original material
When you brush with nano-hydroxyapatite:
• Tiny particles fill in microscopic cracks in enamel
• Helps reduce sensitivity
• Can make teeth look whiter naturally (smoother surface reflects light better)
• Strengthens teeth against future damage
so I ordered 3 pack Boka HA and on everything I love in three days of brushing for 2 minutes twice a day morning at night, do not brush your teeth with tapwater ever!!! It has more chlorine than a swimming pool, calcium lead, and other harsh chemicals that will take away the layer it’s going to build always use bottled water and do not rinse this toothpaste out of your mouth. Let it settle in and pack it into your molars and in between your teeth,it was completely healed and no sensitivity to sugar, hot or cold, it tastes great, and the fluoride free is the only way to go fluoride will destroy your tooth enamel, I gave the other two tubes to my kids and they love it, I am looking forward to less dental appointments for sure!!!!!
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Reviewed in the United States on March 21, 2026
★★★★★ 5
Five stars for BOKA without hesitation.
Size: Pack of 1, 4 Ounce, Set name: A. Ela Mint
I have tried a lot of natural toothpastes over the years and I can honestly say that Boka completely surprised me in the best possible way. From the very first use it felt like I had finally found a toothpaste that balances modern science with a clean ingredient philosophy. You will not be disappointed.
The standout ingredient here is nano hydroxyapatite, which is the same mineral that naturally makes up tooth enamel. That immediately caught my attention because instead of simply masking dental issues it actually supports remineralization. After learning more about nano hydroxyapatite and how it interacts with enamel I felt confident giving this toothpaste a real trial. The texture is smooth and creamy and it spreads easily across the teeth. Some fluoride free toothpastes can feel chalky or thin but this one feels refined and well formulated. It produces a gentle foam that feels pleasant while brushing but never overwhelming.
The flavor is another area where this toothpaste shines. It is refreshing without being harsh or overly minty. My mouth feels clean and balanced after brushing rather than blasted with artificial intensity. That subtle freshness actually lasts much longer than I expected.
After about two weeks of consistent use I started noticing that my teeth felt smoother throughout the day. That polished feeling you normally get right after a dental cleaning lasted longer than usual. My teeth also appeared brighter which was a welcome bonus.
Another thing I appreciate is the ingredient transparency. There are no questionable additives and it is completely fluoride free which is important for people who prefer alternatives that still support enamel health. Knowing that nano hydroxyapatite is widely used in advanced dental care products in other parts of the world made this even more compelling.
The packaging is clean and modern and the tube dispenses easily without making a mess on the cap. It feels like a premium product from start to finish. What really impressed me is how well this toothpaste balances effectiveness, comfort, and thoughtful formulation. It manages to feel gentle while still leaving my teeth incredibly clean and refreshed. If you are looking for a high quality fluoride free toothpaste that focuses on enamel support and a healthier approach to oral care then I highly recommend giving this one a try. It has absolutely earned a permanent place in my daily routine and it is one of the few natural toothpastes I genuinely look forward to using every day.
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Reviewed in the United States on March 12, 2026
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